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Zilmax Type A Medicated Article
Zilmax Type A Medicated Article
This page contains information on Zilmax Type A Medicated Article for veterinary use.
The information provided typically includes the following:
Zilmax Type A Medicated Article Indications
Warnings and cautions for Zilmax Type A Medicated Article
Direction and dosage information for Zilmax Type A Medicated Article
Zilmax Type A Medicated Article
This treatment applies to the following species:
Beef Cattle
Manufacturer: Intervet
(zilpaterol Hydrochloride 4.8%)
Active Drug Ingredient
Zilpaterol hydrochloride 21.77 grams per pound (48 grams per kilogram)
Inert Ingredients
Ground corncobs, surfactant and binder
Important
Must be thoroughly mixed into feeds before use. Follow label directions.
Zilmax Type A Medicated Article Indication
For increased rate of weight gain, improved feed efficiency, and increased carcass leanness in cattle fed in confinement for slaughter during the last 20 to 40 days on feed.
Permitted Claims And Limitations
Carcass Measurements
Effect of Zilpaterol Hydrochloride,
6.8 grams/ton (7.5 ppm)a
Dressing Percentage, %
↑
Hot Carcass Weight, lbs.
↑
Ribeye Area, sq. in.
↑
Yield Grade
↓b
12th Rib Fat Thickness, in.
NC
Marbling Score
NCc
aThe effect of zilpaterol hydrochloride on parameters listed in this table is supported by data generated at the dose tested in the clinical efficacy trials.
NC = No Change, ↑ = increased, ↓ = decreased
bReduction indicates an improvement in Yield Grade.
cZilpaterol hydrochloride has been shown to decrease marbling score when fed for 40 days.
Cattle Fed In Confinement For Slaughter
The approved inclusion rate of zilpaterol hydrochloride is 6.8 grams/ton (7.5 ppm) in Type C Medicated Feed and 60-90 milligrams zilpaterol hydrochloride per head per day on a 90% dry matter basis. The amount of zilpaterol hydrochloride consumed daily by cattle fed in confinement for slaughter will depend upon the consumption rate of the Type C Medicated Feed. Zilpaterol hydrochloride consumption will range between 60 and 90 mg per head per day based on the Type C Medicated Feed consumption rates in the table below.
Cattle Weight
Average Feed Consumption/Head/Day, 90% Dry Matter
Mg Zilpaterol Hydrochloride Consumed Daily by each Animal
Lbs.
Kg
Lbs.1
900
408.2
18.0
61.2
1000
453.6
20.0
68.0
1100
499.0
22.0
74.8
1200
544.3
24.0
81.6
1300
589.7
26.0
88.4
1assumes ad Libitum Intake
mixing Directions
It is recommended that Zilmax® Type A Medicated Article be diluted in a suitable carrier before addition to the final feed. A dilution of 1 part Zilmax® Type A Medicated Article and 9 parts carrier or a 0.68 g zilpaterol/Ib premix are the suggested working premixes. No Type C Medicated Feed should be manufactured with less than 6.8 grams zilpaterol hydrochloride/ton on a 90% dry matter basis. Zilmax® Type A Medicated Article and working premix addition rates for complete feeds of varying dry matter are in the following table.
Complete Feed Percent Dry Matter
Zilpaterol Hydrochloride Level (g/ton)
Zilmax®
Pounds to be Added Per Ton of Feed
1-9 Working Premix
6.8 g Zilpaterol/Ib Working Premix
60
4.53
0.208
2.08
6.66
70
5.29
0.243
2.43
7.78
80
6.04
0.277
2.77
8.88
90
6.80
0.312
3.12
10.00
Thoroughly mix both working premix and finished feed to ensure complete and uniform distribution of the Zilmax® Type A Medicated Article.
Feeding Directions
Feed continuously to cattle fed in confinement for slaughter as the sole ration for the last 20 to 40 days on feed to provide 60 to 90 mg zilpaterol hydrochloride per head per day.
TYPE B FEEDS INTENDED FOR ADDITION TO DRY FEEDS FOR CONFINEMENT CATTLE
- Type B Liquid Feeds should be in a pH range of 3.8 to 7.5
- Type B Liquid Feeds should be recirculated or agitated daily and prior to use for 10 to 20 minutes
- Type B Liquid Feeds can be manufactured containing 68 to 680 g zilpaterol hydrochloride/ton
For liquid feeds stored in recirculating tank systems: Recirculate immediately prior to use for not less than 10 minutes, moving not less than 1 percent of the tank contents per minute from the bottom of the tank to the top. Recirculate daily as described even when not used.
For liquid feeds stored in mechanical, air or other agitation-type tank systems: Agitate immediately prior to use for not less than 10 minutes, creating a turbulence at the bottom of the tank that is visible at the top. Agitate daily as described even when not used.
Before feeding, the Type B Medicated Liquid Feed must be thoroughly mixed with other feed materials to make a complete feed (Type C Medicated Feed). Examples of addition rates to complete feeds are shown in the following table.
Zilpaterol Hydrochloride (g/ton) in Type B Liquid Feed
Addition Rate of Type B Liquid Feed (Ib/ton) to Complete Feed, 90% Dry Matter
Zilpaterol Hydrochloride (g/ton) in Final Complete Feed (Type C Medicated Feed, 90% Dry Matter)
68
200
6.8
340
40
6.8
680
20
6.8
Withdrawal Period
3 days
Zilmax Type A Medicated Article Caution
Not for use in animals intended for breeding. Do not allow horses or other equines access to feed containing zilpaterol. Do not use in veal calves. Do not pellet medicated feeds containing zilpaterol.
You May Notice
Animals receiving zilpaterol hydrochloride may exhibit increased respiratory rate as well as elevated levels of creatine phosphokinase (CPK) and creatinine.
Warning
The active ingredient in Zilmax® is zilpaterol hydrochloride, a beta2-adrenergic agonist. Not for use in humans. An anti-dust process has been applied to the drug product, Zilmax®, in order to greatly reduce inhalation risk. Extended handling tasks with the potential for dust generation require respiratory protection. Wear appropriate skin protection (e.g., impervious gloves, apron, overalls) if there is a potential for extended skin contact. Wear protective eye wear, if there is a potential for eye contact. If accidental eye contact occurs, immediately rinse with water and consult a physician.
Distributed By
Intervet, Inc., Millsboro DE 19966
Made in France
U.S. Patent #4,383,770
U.S. Patent #5,731,028
FOR USE IN THE MANUFACTURE OF MEDICATED FEEDS ONLY.
Store at or below 25°C (77°F)
NADA 141-258, Approved by FDA
Net weight
22.05 lbs. (10 kg)
708481-A
042219 SPI240 01
Nac No.
11063273
INTERVET INC.
29160 INTERVET LANE, BOX 318, MILLSBORO, DE, 19966-0318
Telephone:
800-992-8051
Customer Service:
800-441-8272
Website:
www.intervetusa.com
Email:
Information.USA@intervet.com
Every effort has been made to ensure the accuracy of the Zilmax Type A Medicated Article information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Zilmax Type A Medicated Article product label or package insert.
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