|
Acepromazine Maleate Tablets
Acepromazine Maleate Tablets
This page contains information on Acepromazine Maleate Tablets for veterinary use.
The information provided typically includes the following:
Acepromazine Maleate Tablets Indications
Warnings and cautions for Acepromazine Maleate Tablets
Direction and dosage information for Acepromazine Maleate Tablets
Acepromazine Maleate Tablets
This treatment applies to the following species:
Dogs
Manufacturer: Vedco
Nada No.
117-531 (Injection)/117-532 (Tablets)
Active Ingredient(s)
Each mL contains:
Acepromazine maleate
10 mg
Sodium citrate
0.36%
Citric acid
0.075%
Benzyl alcohol
1.0%
Water for injection
q.s.
Each tablet contains:
Acepromazine
10 mg or 25 mg
Acepromazine Maleate Tablets Indications
As an aid in tranquilization and as a preanesthetic agent in dogs.
ACEPROMAZINE MALEATE INJECTION and TABLETS can be used as an aid in controlling intractable animals during examination, treatment, grooming, x-ray and minor surgical procedures; as a pre-anesthetic agent. Acepromazine maleate has a depressant effect on the central nervous system and therefore causes sedation, muscular relaxation and a reduction in spontaneous activity.
ACEPROMAZINE MALEATE INJECTION is particularly useful as a preanesthetic agent:
1. to enhance and prolong the effects of barbiturates, thus reducing the requirements of general anesthesia;
2. as an adjunct to surgery under local anesthesia.
Pharmacology
Acepromazine maleate, a potent neuroleptic agent with a low order of toxicity, is of particular value in the tranquilization of dogs. Its rapid action and lack of hypnotic effect are added advantages.
Chemistry: 2-acetyl-10-(3-dimethylaminopropyl) phenothiazine hydrogen maleate.
Mode of Action: Acepromazine maleate has a depressant effect on the central nervous system and therefore causes sedation, muscular relaxation and a reduction in spontaneous activity. It acts rapidly, exerting a prompt and pronounced calming effect. It is an effective preanesthetic agent and lowers the dosage requirement of general anesthetics.
Acepromazine Maleate Tablets Dosage And Administration
Injection: ACEPROMAZINE MALEATE INJECTION is a sterile solution which may be given intravenously, intramuscularly or subcutaneously. The dosage should be individualized, depending upon the degree of tranquilization required. As a general rule, the dosage requirement in mg/lb of body weight decreases as the weight of the animal increases. The following schedule may be used as a guide to intravenous, intramuscular or subcutaneous injections:
Dogs: 0.25-0.5 mg per lb. of body weight.
Intravenous doses should be administered slowly, and a period of at least 15 minutes should be allowed for the drug to take full effect.
Tablets: The dosage should be individualized, depending upon the degree of tranquilization required. As a general rule, the dosage requirement in mg/lb of body weight decreases as the weight of the animal increases.
Dogs: 0.25-1.0 mg/lb. of body weight.
Contraindication(s)
Phenothiazines may potentiate the toxicity of organophosphates. Therefore, do not use acepromazine maleate to control tremors associated with organic phosphate poisoning.
Do not use in conjunction with organophosphorus vermifuges or ectoparasiticides, including flea collars.
Do not use with procaine hydrochloride.
Acepromazine Maleate Tablets Caution(s)
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Tranquilizers are potent central nervous system depressants, and they can cause marked sedation with suppression of the sympathetic nervous system.
Tranquilizers can produce prolonged depression or motor restlessness when given in excessive amounts or when given to sensitive animals.
Tranquilizers are additive in action to the actions of other depressants and will potentiate general anesthesia. Tranquilizers should be administered in smaller doses and with greater care during general anesthesia and also to animals exhibiting symptoms of stress, debilitation, cardiac disease, sympathetic blockage, hypovolemia or shock. Acepromazine, like other phenothiazine derivatives, is detoxified in the liver; therefore, it should be used with caution on animals with a previous history of liver dysfunction or leukopenia.
Hypotension can occur after rapid intravenous injection causing cardiovascular collapse.
Epinephrine is contraindicated for the treatment of acute hypotension produced by phenothiazine-derivative tranquilizers since further depression of blood pressure can occur.
Phenothiazines should be used with caution when followed by epidural anesthetic procedures because they may potentiate the arterial hypotensive effects of local anesthetics.
Warning(s)
Federal law prohibits the use of this product in animals intended for human consumption.
Toxicology
Acute and chronic toxicity studies have shown a very low order of toxicity for acepromazine maleate.
Side Effects
A safety study using elevated dosages of ACEPROMAZINE MALEATE INJECTION demonstrated no adverse reactions even when administered at three times the upper limit of the recommended daily dosage (1.5 mg/lb body weight). The clinical observation for this high dosage was mild depression which disappeared in most dogs 24 hours after termination of dosing.
The only occurrence of adverse reaction during numerous clinical trials was a very mild respiratory distress (reverse sneeze) which was transient in nature and had no effect on the desired action of the drug.
When administered intramuscularly, acepromazine maleate causes a brief sensation of stinging comparable with that observed with other phenothiazine tranquilizers.
Presentation
Injection: 50 mL vials.
Tablets: 10 mg tablets and 25 mg tablets - Bottles of 100 and 500.
Nac No.
10940021
VEDCO, INC.
5503 CORPORATE DR., ST. JOSEPH, MO, 64507
Telephone:
816-238-8840
Toll-Free:
888-708-3326 (888-70VEDCO)
Fax:
816-238-1837
Website:
www.vedco.com/dvmonly/
Every effort has been made to ensure the accuracy of the Acepromazine Maleate Tablets information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Acepromazine Maleate Tablets product label or package insert.
Email to a Friend
Typical mistypes for Acepromazine Maleate Tablets
zcepromazine maleate, scepromazine maleate, wcepromazine maleate, qcepromazine maleate, axepromazine maleate, avepromazine maleate, afepromazine maleate, adepromazine maleate, acwpromazine maleate, acspromazine maleate, acdpromazine maleate, acrpromazine maleate, ac4promazine maleate, ac3promazine maleate, aceoromazine maleate, acelromazine maleate, ace-romazine maleate, ace0romazine maleate, acepeomazine maleate, acepdomazine maleate, acepfomazine maleate, aceptomazine maleate, acep5omazine maleate, acep4omazine maleate, aceprimazine maleate, aceprkmazine maleate, aceprlmazine maleate, aceprpmazine maleate, acepr0mazine maleate, acepr9mazine maleate, acepronazine maleate, aceprokazine maleate, aceprojazine maleate, acepromzzine maleate, acepromszine maleate, acepromwzine maleate, acepromqzine maleate, acepromaxine maleate, acepromasine maleate, acepromaaine maleate, acepromazune maleate, acepromazjne maleate, acepromazkne maleate, acepromazone maleate, acepromaz9ne maleate, acepromaz8ne maleate, acepromazibe maleate, acepromazime maleate, acepromazije maleate, acepromazihe maleate, acepromazinw maleate, acepromazins maleate, acepromazind maleate, acepromazinr maleate, acepromazin4 maleate, acepromazin3 maleate, acepromazine naleate, acepromazine kaleate, acepromazine jaleate, acepromazine mzleate, acepromazine msleate, acepromazine mwleate, acepromazine mqleate, acepromazine makeate, acepromazine mapeate, acepromazine maoeate, acepromazine malwate, acepromazine malsate, acepromazine maldate, acepromazine malrate, acepromazine mal4ate, acepromazine mal3ate, acepromazine malezte, acepromazine maleste, acepromazine malewte, acepromazine maleqte, acepromazine maleare, acepromazine maleafe, acepromazine maleage, acepromazine maleaye, acepromazine malea6e, acepromazine malea5e, acepromazine maleatw, acepromazine maleats, acepromazine maleatd, acepromazine maleatr, acepromazine maleat4, acepromazine maleat3, cepromazine maleate, aepromazine maleate, acpromazine maleate, aceromazine maleate, acepomazine maleate, aceprmazine maleate, aceproazine maleate, acepromzine maleate, acepromaine maleate, acepromazne maleate, acepromazie maleate, acepromazin maleate, acepromazinemaleate, acepromazine aleate, acepromazine mleate, acepromazine maeate, acepromazine malate, acepromazine malete, acepromazine maleae, acepromazine maleat, caepromazine maleate, aecpromazine maleate, acperomazine maleate, acerpomazine maleate, acepormazine maleate, aceprmoazine maleate, aceproamzine maleate, acepromzaine maleate, acepromaizne maleate, acepromaznie maleate, acepromazien maleate, acepromazin emaleate, acepromazinem aleate, acepromazine amleate, acepromazine mlaeate, acepromazine maelate, acepromazine malaete, acepromazine maletae, acepromazine maleaet, aacepromazine maleate, accepromazine maleate, aceepromazine maleate, aceppromazine maleate, aceprromazine maleate, aceproomazine maleate, aceprommazine maleate, acepromaazine maleate, acepromazzine maleate, acepromaziine maleate, acepromazinne maleate, acepromazinee maleate, acepromazine maleate, acepromazine mmaleate, acepromazine maaleate, acepromazine malleate, acepromazine maleeate, acepromazine maleaate, acepromazine maleatte, acepromazine maleatee, etc.
Where can I get more information about Drugs, Side Effects, Interactions. We recommend to use http://www.drugspedia.net
|
|
